Blimey Zonda,
if you're getting to MB on Friday, be prepared to sleep standing up!
As for the route, if you want to hammer it on the Autoroute and are comfortable cruising at high speeds then go via Rouen and Paris. If you want a better driving experience, albeit a tad longer, go via Rouen and Alencon. Buy a map on the boat or use a route finder (the RAC and AA have free ones on the web) or check out the 'Useful Info and Maps' section on this forum. Madrid is nice this time of year.
Bon voyage, don't get lost!
H