A good few years ago, I got TOCA Touring Cars game for PS1 and really enjoyed playing it - but it f**ked-me up.
After playing the game, I felt dizzy, particularly when I went to bed (a bit like the effects of alcohol on young teenagers) and it was quite nauseating. I didn't associate the game to the dizziness and just assumed that I had a massive inoperable brain tumor - or something equally jolly and fatal.
When I finally figured it out, I moderated my track time and avoided Donnington, as I believe it was the topography that did my head in. I was perfectly OK with Sonic the Hedgehog, you'll be pleased to learn.